From 15 through 19 September 2025, the Drug Enforcement Administration ran Operation Vape Trail, a week-long enforcement surge at vape shops across its domestic divisions, seizing more than 2.3 million vape devices and cartridges and more than 100 weapons since 15 September.[1][2]

Administrator Terrance Cole said the operation targeted illegal and addictive substances sold in devices that often appeal to young people.[1] The DEA counted 2,357,755 vape pens or cartridges, USD 3,502,905 in currency, USD 5,235,000 in assets, 115 firearms and 106 arrests during the week.[1][2]

The agency highlighted marijuana seizures including nearly 200 pounds of marijuana and more than 50 firearms in two Little Rock investigations, and 70,000 THC cartridges, 30,000 THC edible packages and 15 pounds of marijuana with eleven firearms in a Galveston-area search.[1]